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Elf, P. (2003). Yolk steroid hormones and sex determination in reptiles with tsd. General and Comparative Endocrinology, 132(3), 349–355. 
Added by: Admin (14 Aug 2008 20:36:22 UTC)
Resource type: Journal Article
BibTeX citation key: Elf2003
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Categories: General
Keywords: Chelydra, Chelydra serpentina, Chelydridae, Panzerechsen = crocodilia, Schildkröten = turtles + tortoises, Zeitigung = incubation
Creators: Elf
Collection: General and Comparative Endocrinology
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Abstract     
In reptiles with temperature-dependent sex determination (TSD), the temperature at which the eggs are incubated determines the sex of the offspring. The molecular switch responsible for determining sex in these species has not yet been elucidated. We have examined the dynamics of yolk steroid hormones during embryonic development in the snapping turtle, Chelydra serpentina, and the alligator, Alligator mississippiensis, and have found that yolk estradiol (E(2)) responds differentially to incubation temperature in both of these reptiles. Based upon recently reported roles for E(2) in modulation of steroidogenic factor 1, a transcription factor known to be significant in the sex differentiation process, we hypothesize that yolk E(2) is a link between temperature and the gene expression pathway responsible for sex determination and differentiation in at least some of these species. Here we review the evidence that supports our hypothesis.
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