Literaturdatenbank
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Everaert, D., & Vercauteren, G. , Iron storage disease in aquatic turtles. Unpublished paper presented at 1. International Conference on Avian, Herpetological & Exotic Mammal Medicine.
Added by: Admin (06 Jan 2014 18:24:23 UTC) |
| Resource type: Conference Paper BibTeX citation key: Everaert2013 View all bibliographic details  |
Categories: General Keywords: Chelidae, chemische Untersuchung - chemical analysis, Mesoclemmys gibba, Schildkröten - turtles + tortoises, Veterinärmedizin - veterinary medicine Creators: Everaert, Vercauteren Collection: 1. International Conference on Avian, Herpetological & Exotic Mammal Medicine |
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| Abstract |
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Mesoclemmys gibba A breeder of aquatic turtles had problems of chronic illness with deaths in his turtles. All animals had chronic cutaneous and systemic bacterial and mycotic infections which were unresponsive to therapy. These infections seemed secondary in nature because no primary pathogens could be cultured. Necropsy revealed hepatomegaly which was histopathologically specified as hepatic lipidosis with variable pigment accumulation. Prussian blue stains revealed severe deposition of iron in hepatocytes and Kupffer cells. Source of the iron overload seemed to be a malfunctioning filter and iron overload in the water. Treatment consisted of water changing and silimarin in the food (twice weekly 100 mg/kg). Follow-up of the surviving animals was performed by histopathological examination of liver biopsies. In order to assess the evolution of hepatic iron load, Prussian blue stains were performed and a semi-quantitative method for estimating liver iron was developed. Over a period of 3 months time, hepatocellular iron load decreased and was associated with an increase in Kupffer cell iron. This shift of iron from liver cells to Kupffer cells correlated with clinical improvement
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