Literaturdatenbank
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Papp, T. (2012). Detection and characterisation of adeno-, irido- and paramyxoviruses in reptiles. brief summary of doctoral thesis. Unpublished thesis , Szent István University.
Added by: Admin (06 Jan 2014 18:25:06 UTC) |
| Resource type: Thesis/Dissertation BibTeX citation key: anon2012.15493 View all bibliographic details  |
Categories: General Keywords: Echsen - saurians, Schildkröten - turtles + tortoises, Schlangen - snakes, Stigmochelys pardalis, Testudinidae, Testudo hermanni, Veterinärmedizin - veterinary medicine, Viren - viruses Creators: Papp Publisher: Szent István University |
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| Abstract |
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Testudinidae Geochelone pardalis Testudo hermanni New scientific results 1. Describing two novel squamatid adenoviruses, altogether five reptilian AdV types, that all proved to be members of genus Atadenovirus; supporting the theory of the coevolution and squamate origin of atadenoviruses. 2. Isolating the first pure lizard AdVs in culture, and determining their partial genome sequence; revealing the existence of two fiber genes in atadenoviruses for the very first time. 3. Establishing new methods (qPCR, ISH) for the detection of invertebrate iridoviruses (IIVs) in lizards and prey insects, and applying these methods in transmission trials. 4. Comparison of partial genom segments (14 kb) from 15 genes of IIV isolates from lizards, a scorpion and a cricket; finding mutations, insertions/deletions, and two spots with evidence for recombination compared to the type species CIV; proving a need for taxonomic revision and showing widespread presence of stable variants circulating in Germany. 5. With a transmission study, demonstrating that even the administration of high loads of IIV does not cause the clinical signs in bearded dragons, previously attributed to these viruses. 6. Molecular characterisation of novel paramyxovirus isolates from snakes, lizards, and (the first time) a tortoise; supporting their classification as members of the new genus Ferlavirus; the tortoise ferlavirus being the most ancient branch, while the other squamatid isolates separating into a new and two redefined groups. The genus characteristic U gene was undetectable in the tortoise isolate. 7. Describing fifteen ferlavirus sequence variants with surprisingly high (27.5%) prevalence, and (the first time) revealing concurrent infection with more than one PMV types in snake specimens and/or populations and in a leopard tortoise.
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