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Bodri, M. S., Nolan, T. J., & Skeeba, S. J. (1993). Safety of milbemycin (a3-a4 oxime) in chelonians. Journal of Zoo and Wildlife Medicine, 24(2), 171–174. 
Added by: Admin (23 Aug 2008 15:32:52 UTC)
Resource type: Journal Article
BibTeX citation key: Bodri1993
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Categories: General
Keywords: Emydidae, Parasiten = parasites, Pseudemys, Schildkröten = turtles + tortoises, Terrapene, Terrapene carolina, Terrapene ornata, Trachemys, Trachemys ornata, Trachemys scripta, Trachemys terrapen, Veterinärmedizin = veterinary medicine
Creators: Bodri, Nolan, Skeeba
Collection: Journal of Zoo and Wildlife Medicine
Views: 3/935
Views index: 16%
Popularity index: 4%
Abstract     
Red-eared sliders (Pseudemys scripta elegans) were given ivermectin (0.2 mg/kg), milbemycin (A3-A4 oxime) (0.5 or 1.0 mg/kg), or propylene glycol (0.2 ml/kg) p.o. to determine the sensitivity of these animals to these drugs and from the data to infer the safety of milbemycin. Half of the ivermectin-treated turtles showed paresis or flaccid paralysis. One animal died, and histology of the liver indicated a diffuse fatty change. No clinical evidence of toxicity was noted in the milbemycin-treated animals. A group of red-eared sliders and 6 Gulf Coast box turtles (Terrapene carolina major) were given 0.5 mg/kg milbemycin s.c. in the front leg. No deleterious effects or site reactions were clinically detected. Five ornate box turtles (T. c. ornata) with patent helminth infestations were treated s.c. with 0.25 mg/kg milbemycin and ceased to shed eggs in their faeces following 1 or 2 doses.
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